Effect of varying laser parameters on in-vitro ablation of porcine sclera with Ho:YAG laser

Vani R. Pergadia; Sandor G. Vari M.D.; Wei-Qiang Shi; Michael C. Fishbein M.D.; Warren S. Grundfest M.D.

doi:10.1117/12.147529

24 June 1993 Effect of varying laser parameters on in-vitro ablation of porcine sclera with Ho:YAG laser

Vani R. Pergadia, Sandor G. Vari M.D., Wei-Qiang Shi, Michael C. Fishbein M.D., Warren S. Grundfest M.D.

Proceedings Volume 1877, Ophthalmic Technologies III; (1993) https://doi.org/10.1117/12.147529
Event: OE/LASE'93: Optics, Electro-Optics, and Laser Applications in Scienceand Engineering, 1993, Los Angeles, CA, United States

Abstract

The effect of various laser parameters on the ablation rate and the resulting thermal damage on porcine scleral tissue by the Ho:YAG laser was tested. We compared the ablation rate and the thermal damage with varying fluences, fiber core diameters and pulse durations. A Ho:YAG laser operating at a wavelength of 2.1 micrometers at a repetition rate of 2 Hz was used. The ablation rate for the tissue was calculated as the ratio of the number of pulses needed to perforate the sample to the sample thickness (micrometers /pulse +/- standard deviation). The lateral thermal damage depths were quantified by ocular micrometry. Our results suggest that with the Ho:YAG (2.1 micrometers ) laser the ablation rate increases linearly with radiant exposure, but the change in radiant exposure does not significantly affect thermal damage. Different pulse durations generate small changes in ablation rate, but no change in thermal damage. An increase in the irradiated area enhances the ablation rate and thermal damage.

Citation Download Citation

Vani R. Pergadia, Sandor G. Vari M.D., Wei-Qiang Shi, Michael C. Fishbein M.D., and Warren S. Grundfest M.D. "Effect of varying laser parameters on in-vitro ablation of porcine sclera with Ho:YAG laser", Proc. SPIE 1877, Ophthalmic Technologies III, (24 June 1993); https://doi.org/10.1117/12.147529

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