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23 June 1993 Gas production in tissue phantoms and tissue by XeCl excimer laser: effect of beam delivery system geometry
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Proceedings Volume 1878, Diagnostic and Therapeutic Cardiovascular Interventions III; (1993) https://doi.org/10.1117/12.146585
Event: OE/LASE'93: Optics, Electro-Optics, and Laser Applications in Scienceand Engineering, 1993, Los Angeles, CA, United States
Abstract
In excimer laser coronary angioplasty (ELCA) an XeCl excimer laser at 308 nm is used to ablate atherosclerotic plaque in a stenosed coronary artery. In previous experiments we have seen that during ablation of cardiovascular tissues under saline, there is always a release of a stream of insoluble gas bubbles. We believe that this gas plays a crucial role in the understanding of the recanalization process in ELCA where a laser beam delivery catheter is brought in contact with the plaque in a tight space. It is well conceivable that the gas may help to recanalize an artery as a kind of dottering effect but especially in a tight stenosis the gas accumulation may enhance the damage to the vessel wall. The aim of the study was to investigate the dependency of the gas production by a XeCl excimer laser on the energy density and the diameter of the beam delivery system, to establish whether the effects of gas could be minimized or would be independent on the beam delivery system.
© (1993) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Geert H. Gijsbers, Hans G. Jenniskens, Geert G. Verhoofstad, and Martin J. C. van Gemert "Gas production in tissue phantoms and tissue by XeCl excimer laser: effect of beam delivery system geometry", Proc. SPIE 1878, Diagnostic and Therapeutic Cardiovascular Interventions III, (23 June 1993); https://doi.org/10.1117/12.146585
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