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7 July 1993 Dependence of laser photocoagulation on interstitial delivery parameters
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Proceedings Volume 1882, Laser-Tissue Interaction IV; (1993)
Event: OE/LASE'93: Optics, Electro-Optics, and Laser Applications in Scienceand Engineering, 1993, Los Angeles, CA, United States
Interstitial laser photocoagulation (ILP) was performed ex vivo between tissue slabs by delivering continuous-wave laser energy from an optical fiber (400 micrometers core, plane-cut, 5 mm cladding stripped) either directly, or by depositing the energy into a 2.4 mm diameter steel sphere mounted on the fiber tip. The dependence of the size and nature of the resulting thermal coagulation lesions on the following variables were assessed: (1) energy source: Nd:YAG - 532 nm, 1064 nm +/- steel sphere, (2) tissue type: porcine muscle (light), bovine muscle (dark), (3) delivered power: P equals 1.5 - 3.0 W (porcine), 1.0 - 2.5 W (bovine), (4) exposure duration: T equals 300 - 700 s. The resulting cross-sectional ILP lesions are summarized as follows: 532 nm: elongated; central charring in bovine and porcine at all powers. 1064 nm: circular; central charring only in bovine for P >= 2.0 W, T >= 500 s, sphere: circular; central charring in bovine for P >= 1.5 W and porcine for P >= 2.0 W. These experiments confirm a recent report suggesting ILP lesion size decreases as optical penetration increases. The results indicate that ILP lesions of clinically useful size (diameter >= 8 mm) must necessarily involve central charring in heavily pigmented tissues, but ILP lesions greater than 10 mm diameter can be made without charring in lightly pigmented tissues by delivering 3.0 W of 1064 nm laser energy for 700 s.
© (1993) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Douglas Robert Wyman, Brian C. Wilson, and Kathryn Adams "Dependence of laser photocoagulation on interstitial delivery parameters", Proc. SPIE 1882, Laser-Tissue Interaction IV, (7 July 1993);

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