Modern surgery widely uses both laser and low frequency ultrasonic techniques together with various modifications of contact instruments. This paper describes for the first time the feasibility of different combinations of these techniques in the medical practice. Comparative analysis of laser and ultrasound systems show that they can essentially supplement each other and, in combination, bring new efficacious results. Over time during surgical procedures, both ultrasound and lasers are used one after the other. It is also possible to use both techniques simultaneously from separate devices and separate contact tips. However combination of laser and ultrasound in one unit and in one contact tip using optical fiber and acoustic waveguide for delivery of laser and ultrasound energy is more efficient.