17 June 1993 Partially developed speckle-fields dynamics for blood microcirculation and biovibration parameters measurement
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Proceedings Volume 1922, Laser Study of Macroscopic Biosystems; (1993) https://doi.org/10.1117/12.146211
Event: Laser Spectroscopy of Biomolecules: 4th International Conference on Laser Applications in Life Sciences, 1992, Jyvaskyla, Finland
In this paper diffraction of focused laser beams in thin blood vessels is discussed. A theoretical description of this process is given, a number of model experiments are carried out. Relations establishing the dependence of the scattered field parameters on the characteristics of blood flow in vessels, the diameter of which is about erythrocytes size, are obtained. The relations between the optical signal characteristics and the position of the observation point of speckle- field is discussed. The investigations of the dependence of the space-time projection structure of the speckle-interferometer output signal on heart disease seriousness have been carried out. The novel technique of heart disease diagnostic is suggested. The results of experimental investigations of pulse waves, using the differential speckle-interferometer, are present. The traditional speckle-interferometer Michelson type and differential speckle-interferometer for cardiovibration measurements are compared. Difficulties, appearing from use of the suggested diagnostic method, are analyzed and ways of their elimination are found.
© (1993) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Sergey S. Ulyanov, Valery V. Tuchin, "Partially developed speckle-fields dynamics for blood microcirculation and biovibration parameters measurement", Proc. SPIE 1922, Laser Study of Macroscopic Biosystems, (17 June 1993); doi: 10.1117/12.146211; https://doi.org/10.1117/12.146211

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