1 March 1994 Pharmakokinetics of 132-hydroxy-bacteriopheophorbide: a methyl ester studied by fluorescence spectroscopy on Lewis lung carcinoma bearing mice
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Proceedings Volume 2078, Photodynamic Therapy of Cancer; (1994) https://doi.org/10.1117/12.168685
Event: Europto Biomedical Optics '93, 1993, Budapest, Hungary
Abstract
The pharmacokinetics of 132-hydroxy-bacteriopheophorbide a methyl ester (OH-BPME) was studied on Lewis lung carcinoma bearing mice by fluorescence spectroscopy. The sensitizer distribution in different organs and in the tumor was investigated in dependence on the incubation time. A very fast cleaning of the blood and the skin was observed. The results of our investigations suggest that PDT using OH-BPME could be effective at sensitizer incubation times of about 12 h.
© (1994) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Beate Roeder, Beate Roeder, Cathrin Dressler, Cathrin Dressler, B. Fuchs, B. Fuchs, Roland Hagemann, Roland Hagemann, Hans-Peter Berlien, Hans-Peter Berlien, Christian Nowak, Christian Nowak, Joerg G. Moser, Joerg G. Moser, } "Pharmakokinetics of 132-hydroxy-bacteriopheophorbide: a methyl ester studied by fluorescence spectroscopy on Lewis lung carcinoma bearing mice", Proc. SPIE 2078, Photodynamic Therapy of Cancer, (1 March 1994); doi: 10.1117/12.168685; https://doi.org/10.1117/12.168685
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