1 March 1994 Photochemical inactivation of viruses by antibody conjugates of compounds generating singlet oxygen
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Proceedings Volume 2078, Photodynamic Therapy of Cancer; (1994) https://doi.org/10.1117/12.168670
Event: Europto Biomedical Optics '93, 1993, Budapest, Hungary
Abstract
For the first time a method is proposed for targeted destruction of viral particles with a photoimmuno-toxin. The photoinununotoxin is a conjugate of antibodies and dimethoxy haematoporphyrin (a potent singlet oxygen generator), binding with the viral particle and upon illumination with visible light inactivating the virus by singlet oxygen. The method can be used to combat viral infection in humans and to prevent lysis of industrial micro-organisms by lysogenic bacteriophage strains.
© (1994) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Alexander P. Savitsky, Alexander P. Savitsky, Andrey I. Tourkin, Andrey I. Tourkin, Elena V. Tourkina, Elena V. Tourkina, Tatyana V. Cherednikova, Tatyana V. Cherednikova, Gely V. Ponomarev, Gely V. Ponomarev, Boris F. Poglazov, Boris F. Poglazov, } "Photochemical inactivation of viruses by antibody conjugates of compounds generating singlet oxygen", Proc. SPIE 2078, Photodynamic Therapy of Cancer, (1 March 1994); doi: 10.1117/12.168670; https://doi.org/10.1117/12.168670
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