1 March 1994 Photophysics of sulphonated aluminum phthalocyanines in reversed micelles
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Proceedings Volume 2078, Photodynamic Therapy of Cancer; (1994) https://doi.org/10.1117/12.168691
Event: Europto Biomedical Optics '93, 1993, Budapest, Hungary
Abstract
The photophysics of sulphonated aluminum phthalocyanines, AlPcSn (n equals 0, 1, 2, 3 or 4), potential second-generation phototherapeutic agents for tumors, in cationic reversed micelles of benzyl ammonium hexadecyl chloride (BHDC) and anionic reversed micelles of sodium di(2-ethylhexyl) sulphosuccinate (AOT) have been investigated. Absorption spectroscopy, as well as steady state and time-resolved fluorescence emission studies, indicate that in BHDC the di- and tri-sulphonated derivatives are essentially monomeric whereas in AOT only the di-sulphonated phthalocyanine was found to be monomeric. The distribution of AlPcSn in the reversed micelles, which appears to be strongly influenced by the extent of sulphonation and the environment of the reversed micelle, is discussed. It is anticipated that extrapolation can then be made to heterogeneous systems such as are found in biomembranes.
© (1994) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Suman Dhami, Suman Dhami, Juan J. Cosa, Juan J. Cosa, Steven M. Bishop, Steven M. Bishop, Mary S. C. Simpson, Mary S. C. Simpson, David Phillips, David Phillips, } "Photophysics of sulphonated aluminum phthalocyanines in reversed micelles", Proc. SPIE 2078, Photodynamic Therapy of Cancer, (1 March 1994); doi: 10.1117/12.168691; https://doi.org/10.1117/12.168691
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