1 March 1994 Subcellular distribution of photodynamic sensitizers
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Proceedings Volume 2078, Photodynamic Therapy of Cancer; (1994) https://doi.org/10.1117/12.168661
Event: Europto Biomedical Optics '93, 1993, Budapest, Hungary
Abstract
Various microscopic methods were established to measure the subcellular distribution and light-induced reactions of photosensitizing porphyrins. These methods include high resolution video microscopy, microspectrofluorometry, as well as time-resolved and time-gated fluorescence spectroscopy. By using these techniques, different components of hydrophylic and hydrophobic photosensitizers (e.g. monomers, aggregates, ionic species) were localized, and their intracellular reactions -- re-distribution, formation of photoproducts, pH-dependent spectral changes -- were studied.
© (1994) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Herbert Schneckenburger, Michael H. Gschwend, Karsten Koenig, Angelika C. Rueck, Reinhard Sailer, Wolfgang S. L. Strauss, "Subcellular distribution of photodynamic sensitizers", Proc. SPIE 2078, Photodynamic Therapy of Cancer, (1 March 1994); doi: 10.1117/12.168661; https://doi.org/10.1117/12.168661
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