Subcellular distribution of photodynamic sensitizers

Herbert Schneckenburger; Michael H. Gschwend; Karsten Koenig; Angelika C. Rueck; Reinhard Sailer; Wolfgang S. L. Strauss

doi:10.1117/12.168661

1 March 1994 Subcellular distribution of photodynamic sensitizers

Herbert Schneckenburger, Michael H. Gschwend, Karsten Koenig, Angelika C. Rueck, Reinhard Sailer, Wolfgang S. L. Strauss

Author Affiliations +

Proceedings Volume 2078, Photodynamic Therapy of Cancer; (1994) https://doi.org/10.1117/12.168661
Event: Europto Biomedical Optics '93, 1993, Budapest, Hungary

Abstract

Various microscopic methods were established to measure the subcellular distribution and light-induced reactions of photosensitizing porphyrins. These methods include high resolution video microscopy, microspectrofluorometry, as well as time-resolved and time-gated fluorescence spectroscopy. By using these techniques, different components of hydrophylic and hydrophobic photosensitizers (e.g. monomers, aggregates, ionic species) were localized, and their intracellular reactions -- re-distribution, formation of photoproducts, pH-dependent spectral changes -- were studied.

Citation Download Citation

Herbert Schneckenburger, Michael H. Gschwend, Karsten Koenig, Angelika C. Rueck, Reinhard Sailer, and Wolfgang S. L. Strauss "Subcellular distribution of photodynamic sensitizers", Proc. SPIE 2078, Photodynamic Therapy of Cancer, (1 March 1994); https://doi.org/10.1117/12.168661

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available