Paper
23 June 1994 Light-scattering from a tenuous cylindrical matrix and the reflectance of the retinal nerve fiber layer
Qienyuan Zhou, Robert W. Knighton
Author Affiliations +
Proceedings Volume 2126, Ophthalmic Technologies IV; (1994) https://doi.org/10.1117/12.178544
Event: OE/LASE '94, 1994, Los Angeles, CA, United States
Abstract
Evaluation of the retinal nerve fiber layer (RNFL) is important in the diagnosis of glaucoma and other optic nerve diseases. To aid understanding of the mechanism of RNFL reflectance, anatomical data were obtained from electron micrographs of cross- sections of amphibian RNFL and possible and possible scattering structures (axonal membranes, microtubules, and neurofilaments) were modeled as arrays of parallel thin fibers. Microtubules and neurofilaments are already thin fibers, and axonal membranes were decomposed into arrays of adjacent parallel fibers. Internal fields were assigned to each fiber by means of Born approximation or according to rules that depended on membrane orientation. Far field scattering was then calculated by field summation. Calculated scattering was much larger from axonal membranes than from microtubules or neurofilaments. Calculated spectra from 400- 700 nm showed increased scattering at shorter wavelengths for both axonal membranes and microtubules. Calculated backscattering from axonal membranes was approximately equal for incident light polarized parallel (TM mode) and perpendicular (TE mode) to the cylinder axis, but from microtubules TE mode scattering was less than TM mode.
© (1994) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Qienyuan Zhou and Robert W. Knighton "Light-scattering from a tenuous cylindrical matrix and the reflectance of the retinal nerve fiber layer", Proc. SPIE 2126, Ophthalmic Technologies IV, (23 June 1994); https://doi.org/10.1117/12.178544
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KEYWORDS
Scattering

Light scattering

Reflectivity

Nerve

Refractive index

Optic nerve

Axons

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