7 September 1994 Effect of clenbuterol on cardiopulmonary parameters and intramuscular blood flow by laser Doppler flowmetry in anesthetized ponies
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Abstract
The cardiopulmonary affects and the affects on muscular microperfusion of the beta adrenergic agonist, clenbuterol (0.8 mcg/kg intravenously), were investigated in dorsally recumbent anesthetized ponies. Muscle microcirculation was measured by laser Doppler flowmetry, utilizing fine optical fiber probes. Other measurements included heart rate, cardiac output, arterial blood pressure, and arterial blood gas tensions. Clenbuterol injection caused a regular, but transitory rise in muscle microcirculation, an increase in heart rate, and cardiac output and a decrease in mean arterial blood pressure. Clenbuterol did appear to prevent the continuing fall in arterial blood oxygen tensions seen in the treatment groups, but had only minimal affects in reversing the hypoxia already present.
© (1994) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Yong Hoon Lee, Kathleen Williamson Clarke, Hatim I. K. Alibhai, "Effect of clenbuterol on cardiopulmonary parameters and intramuscular blood flow by laser Doppler flowmetry in anesthetized ponies", Proc. SPIE 2128, Laser Surgery: Advanced Characterization, Therapeutics, and Systems IV, (7 September 1994); doi: 10.1117/12.184948; https://doi.org/10.1117/12.184948
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