7 September 1994 Intraoperative photodynamic therapy on spontaneous canine nasal tumors
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Promising results obtained by photodynamic therapy (PDT) with porphyrins on superficial spontaneous canine tumors suggested the experiment of this technique on intracavitary tumors, specifically at the endonasal site. The supposed neoplastic residual bed was irradiated directly during surgery at the end of the debulking. Five dogs referred to the surgical department of the veterinary school, University of Milan and affected by endonasal neoplasias were submitted to PDT after radiologic and cyto-histologic diagnosis and TNM stadiation. All the selected tumors were included in the clinical stage 1 (T1NOMO). Mean and median survival time (from the day of treatment) were 11.6 - 5.4 and 12 months, respectively. Different staging of the treated tumors limits the possibility of an objective comparison with other alternative therapeutic procedures.
© (1994) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Diego Fonda, Diego Fonda, Carlo Maria Mortellaro, Carlo Maria Mortellaro, Stefano Romussi, Stefano Romussi, Paola Taroni, Paola Taroni, Rinaldo Cubeddu, Rinaldo Cubeddu, } "Intraoperative photodynamic therapy on spontaneous canine nasal tumors", Proc. SPIE 2128, Laser Surgery: Advanced Characterization, Therapeutics, and Systems IV, (7 September 1994); doi: 10.1117/12.184947; https://doi.org/10.1117/12.184947

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