A sensor capable of simultaneous imaging and pH measurements has been prepared by coating the distal tip of a single imaging fiber with a pH sensitive material. The coated fiber is fabricated using photochemical polymerization with a spin coating technique, and results in a fairly uniform coating of polyHEMA/fluorescein on the order of 10 micrometers thick. Performance data, and imaging capabilities, as well as instrumentation requirements and deposition chemistry, are discussed.
Karen S. Bronk,
David R. Walt,
"Development of sensor arrays using fiber optic imaging bundles", Proc. SPIE 2131, Biomedical Fiber Optic Instrumentation, (28 July 1994); doi: 10.1117/12.180748; https://doi.org/10.1117/12.180748