Copper vapor lasers (CVLs) are widely used in the treatment and management of vascular, benign pigmented, and cutaneous lesions and malformations. Recent improvements in laser output powers and delivery systems, including automated scanning devices, have greatly increased the utility of these lasers. Increased laser powers have enabled the duration of treatment exposures to be shortened allowing better target tissue thermal relaxation time matching for improved clinical results. Product enhancements, including reduced warm-up times, and improved manufacturing methods have significantly reduced the cost of this technology which has in turn greatly increased the private office acceptance of CVLs. Gold vapor lasers and copper vapor lasers pumped dye lasers are also extensively used in photodynamic therapy clinical trials.