Charge-coupled device and neural-network-based instrument for the noninvasive determination of tissue optical properties in vivo

Thomas J. Farrell; Michael S. Patterson; Joseph E. Hayward; Brian C. Wilson; Elsa R. Beck D.V.M.

doi:10.1117/12.175987

19 May 1994 Charge-coupled device and neural-network-based instrument for the noninvasive determination of tissue optical properties in vivo

Thomas J. Farrell, Michael S. Patterson, Joseph E. Hayward, Brian C. Wilson, Elsa R. Beck D.V.M.

Author Affiliations +

Proceedings Volume 2135, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases; (1994) https://doi.org/10.1117/12.175987
Event: OE/LASE '94, 1994, Los Angeles, CA, United States

Abstract

We describe an instrument which will permit simultaneous collection of radial resolved reflectance over the spectral range 600-1000 nm and a neural network algorithm which permits real- time analysis of the data. The in vivo performance of the instrument is presently under investigation. Data will be presented illustrating the performance of the instrument over the useful optical spectrum for certain tissues of interest. In addition the derived tissue concentrations of photosensitizers will be compared with those obtained using chemical extraction techniques on excised tissue samples.

Citation Download Citation

Thomas J. Farrell, Michael S. Patterson, Joseph E. Hayward, Brian C. Wilson, and Elsa R. Beck D.V.M. "Charge-coupled device and neural-network-based instrument for the noninvasive determination of tissue optical properties in vivo", Proc. SPIE 2135, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases, (19 May 1994); https://doi.org/10.1117/12.175987

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