19 May 1994 Detection of an object inside a phantom tissue using a spatial filter
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Proceedings Volume 2135, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases; (1994); doi: 10.1117/12.175994
Event: OE/LASE '94, 1994, Los Angeles, CA, United States
Abstract
We report the detection of an object inside a phantom tissue using a spatial filter and a 5-mW He-Ne Laser. The phantom tissue is composed of 8% scattering polystyrene spheres and is diluted to different concentrations in water. The solution is placed inside of a cuvette of length 5 cm and width 5 cm. The spatial filter, composed of a 4-cm plano-convex lens and a 10-micrometers pinhole, is able to extract ballistic and quasi-ballistic photons from the transmitted light. A photomultiplier tube is used for detection, and a lock-in amplifier is used to reduce the amount of noise in the signal. We are able to detect the object in a phantom tissue of 20 mean free paths [mfp] with a contrast of 99.0%. The contrast in a tissue with 30 mfp is 22.7%.
© (1994) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Dawn V. Stephens, Frank K. Tittel, Lihong V. Wang, Andreas H. Hielscher, Steven L. Jacques, "Detection of an object inside a phantom tissue using a spatial filter", Proc. SPIE 2135, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases, (19 May 1994); doi: 10.1117/12.175994; http://dx.doi.org/10.1117/12.175994
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KEYWORDS
Tissues

Tissue optics

Spatial filters

Cancer

Ultrasonography

Optical spheres

Laser tissue interaction

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