21 July 1994 Overview of a novel point of care instrument system for measuring whole blood Prothrombin time
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Proceedings Volume 2136, Biochemical Diagnostic Instrumentation; (1994) https://doi.org/10.1117/12.180788
Event: OE/LASE '94, 1994, Los Angeles, CA, United States
This paper describes a new diagnostic instrument which uses magnetic modulation of an optical signal to rapidly measure whole blood Prothrombin time. The new instrument improves diagnosing and level monitoring by allowing accurate, rapid, low cost near patient testing. The measurement system consists of five major components: a control system; a user interface, a disposable-strip laminate architecture with proprietary chemistry which interacts with a time-varying magnetic field and accelerates the coagulation reaction; an optical measurement module -- the optics assembly of the instrument contains a heater, electromagnet, dc magnet, and numerous reflective/transmissive radiometric sensor systems; and a calibration-instrument using a custom developed test device which accurately simulates the coagulation reaction's induced optical properties. The theory of operation of the coagulation assay system and optical measurement module is describe and typical data and performance metrics are presented. 6
© (1994) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Greg P. Carpenter, Greg P. Carpenter, T. Gary Neel, T. Gary Neel, James R. Parker, James R. Parker, "Overview of a novel point of care instrument system for measuring whole blood Prothrombin time", Proc. SPIE 2136, Biochemical Diagnostic Instrumentation, (21 July 1994); doi: 10.1117/12.180788; https://doi.org/10.1117/12.180788

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