Instrumentation aspects for spaceborn critical point and aggregation studies on the basis of various test data gathered by ground laboratory equipment

Matthias Dieckmann; Karsten Dierks; Thomas Weigel

doi:10.1117/12.188083

30 September 1994 Instrumentation aspects for spaceborn critical point and aggregation studies on the basis of various test data gathered by ground laboratory equipment

Matthias Dieckmann, Karsten Dierks, Thomas Weigel

Author Affiliations +

Proceedings Volume 2210, Space Optics 1994: Space Instrumentation and Spacecraft Optics; (1994) https://doi.org/10.1117/12.188083
Event: Space Optics '94, 1994, Garmisch, Germany

Abstract

Time averaged static light scattering (SLS) intensity collections on suspensions with defined particle dimensions and concentrations were achieved by utilization of the Zeiss SG 100 goniometer scatterometer. The bidirectional straylight distribution functions (BSDF) of suspensions containing 36 mg/ml lysozyme with NaCl-buffer and latex standards with diameters of 90 nm, 270 nm, 310 nm, 500 nm and 3100 nm in various concentrations are given. The measurements clearly reveal absence of complex Mie light intensity distributions to which presence is often referred to. Presented data collection achieved with commercial equipment would enable extraction of instrument designs appropriate for operation of dynamic light scattering (DLS) in reduced gravity environments. Optoelectronics and fiber optics of the multiangle Coulter N4MD submicron analyzer are concisely described and analyzed. DLS is introduced concerning baseline determination and applied evaluation procedures. Consequences of analysis yielded potential advancements to two optomechanics (optrode; lens protein analyzer LPA and goniometer device; DIMINIGON-A). Their operation is demonstrated in linkage with a 288 real time correlator (ALV-Langen). Experimental results achieved during aggregation and crystallization of lysozyme together with detection of intercalation between DNA and doxorubicin (antitumor therapeutics) are included. Results of viscosity measurements under low shear rates as function of the protein concentrations will be presented.

Citation Download Citation

Matthias Dieckmann, Karsten Dierks, and Thomas Weigel "Instrumentation aspects for spaceborn critical point and aggregation studies on the basis of various test data gathered by ground laboratory equipment", Proc. SPIE 2210, Space Optics 1994: Space Instrumentation and Spacecraft Optics, (30 September 1994); https://doi.org/10.1117/12.188083

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
14 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Particles

Scattering

Light scattering

Latex

Optical correlators

Crystals

Backscatter

Show All Keywords

Keywords/Phrases

Search In:

Publication Years