To remotely image objects in a lossy inhomogeneous material requires advance knowledge on the geometry and electrical properties of the host material, as well as the positions of the transmitter and receiver relative to the host structure. Separate measurements with different apparatus are often required for obtaining this essential information. In this paper, we present a systematic approach to simultaneously retrieve information regarding both the target and the host material with a single synthetic aperture measurement. A variety of techniques have been invoked in this composite approach to extract the location, orientation, and mean propagation constant of the host structure. These parameters are subsequently used in the image focusing algorithm. It is shown that a substantial improvement in the image quality over a conventional pulse-echo system can be achieved.