6 October 1994 Biosensor technology for the detection of illegal drugs I: objectives, preparatory work, and drug enrichment
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In a joint project of Deutsche Aerospace, Boehringer Mannheim and the University of Potsdam portable devices for the detection of illegal drugs, based on biosensor technology, are being developed. The concept enrichment of the drug from the gas phase and detection by immunological means. This publication covers the description of our objectives, preparatory work and results concerning enrichment of drugs from the gas phase. Vapor pressures of cocaine and cannabinoids have been determined. A test gas generator has been constructed which allows for reproducible preparation of cocaine concentrations between 2 ng/l and 2 pg/l. Coupling of a thermodesorption unit with GC/MS has been established for reference analysis. As another analytical tool, an ELISA with a lower detection limit of about 0,5 pg cocaine/assay has been developed. Applying fleece-type adsorbers, enrichment factors for cocaine in the range of 105 have been realized. No significant interference was found with potentially disturbing substances.
© (1994) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Reinhold Hilpert, Florian Binder, Michael Grol, Klaus Hallermayer, Hans-Peter Josel, Christian Klein, Josef Maier, Helmut Oberpriller, Josef Ritter, Frieder W. Scheller, "Biosensor technology for the detection of illegal drugs I: objectives, preparatory work, and drug enrichment", Proc. SPIE 2276, Cargo Inspection Technologies, (6 October 1994); doi: 10.1117/12.189162; https://doi.org/10.1117/12.189162



Aerospace engineering





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