A total of 148 volatile compounds were identified from the laser plume produced by a 10 W CO2 laser upon irradiation of pig liver. Structure elucidation was carried out by coupled gas chromatography mass spectrometry using reference samples. The identified compounds include hydrocarbons, alcohols, aldehydes, acids, esters, amides nitriles, ketones, furans, phenols, pyrazines, pyridines, and sulphur-compounds. Toluene, styrene, methylpyrazine, benzaldehyde, benzylcyanide, 4-methylphenol, indol and scatol for the major components of the pyrolysis products; derivatives may also reach higher concentrations. An interesting group of O/N-compounds with closely related chemical structures remained unknown.