4 January 1995 Fluorescence spectroscopy in combination with reflectance measurements in human skin examination: what for and how
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Proceedings Volume 2324, Optical Biopsy and Fluorescence Spectroscopy and Imaging; (1995) https://doi.org/10.1117/12.198712
Event: International Symposium on Biomedical Optics Europe '94, 1994, Lille, France
Abstract
Reflectance and fluorescence spectroscopy are successfully used for skin disease diagnostics. Human skin optical parameters are defined by its turbid, scattering properties with nonuniform absorption and fluorescence chromophores distribution, its multilayered structure, and variability under different physiological and pathological conditions. Theoretical modeling of light propagation in skin could improve the understanding of these conditions and may be useful in the interpretation of in vivo reflectance and autofluorescence spectra. In the present work the temporal behavior of in vivo reflectance and autofluorescence (excitation wavelength 337 nm) spectra of human skin under ultraviolet irradiation and external mechanical pressure were investigated. Experimental results and Monte Carlo modeling of light distribution in skin were compared and demonstrated good agreements. Combination of diffuse reflectance and autofluorescence measurements is a very promising technique for precise erythema and pigmentation of the human skin evaluation.
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Sergei R. Utz, Sergei R. Utz, Yurii P. Sinichkin, Yurii P. Sinichkin, Igor Victorovich Meglinski, Igor Victorovich Meglinski, Helena A. Pilipenko, Helena A. Pilipenko, } "Fluorescence spectroscopy in combination with reflectance measurements in human skin examination: what for and how", Proc. SPIE 2324, Optical Biopsy and Fluorescence Spectroscopy and Imaging, (4 January 1995); doi: 10.1117/12.198712; https://doi.org/10.1117/12.198712
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