12 January 1995 Chlorin-type photosensitizers derived from vinyl porphyrins
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Proceedings Volume 2325, Photodynamic Therapy of Cancer II; (1995) https://doi.org/10.1117/12.199160
Event: International Symposium on Biomedical Optics Europe '94, 1994, Lille, France
Abstract
The reaction of singlet oxygen with vinyl porphyrins, which was first described in the case of protoporphyrin, is reinvestigated as a route to chlorin type molecules. Various dicarboxylic chlorins were thus prepared and characterized for their chemical and photosensitizing properties. All of them efficiently photosensitize the production of singlet oxygen. Some of these compounds might be formed during photodynamic therapy with hematoporphyrin derivative or Photofrin. Their biological relevance is discussed.
© (1995) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Daniel Brault, Daniel Brault, B. Aveline, B. Aveline, O. Delgado, O. Delgado, Christine Vever-Bizet, Christine Vever-Bizet, } "Chlorin-type photosensitizers derived from vinyl porphyrins", Proc. SPIE 2325, Photodynamic Therapy of Cancer II, (12 January 1995); doi: 10.1117/12.199160; https://doi.org/10.1117/12.199160
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