12 January 1995 In vitro photobiological activity of a new series of photosensitizers: the glycoconjugated porphyrins
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Proceedings Volume 2325, Photodynamic Therapy of Cancer II; (1995) https://doi.org/10.1117/12.199141
Event: International Symposium on Biomedical Optics Europe '94, 1994, Lille, France
Abstract
The in vitro photodynamic inactivation of a KB cell line is studied using a large series of neutral water-soluble glycosylated porphyrins. These compounds in which hydrophilic glycosyl moieties and hydrophobic substituents are linked at the meso positions, generate singlet oxygen in roughly 70%. Results reveal that the phototoxicity is markedly dependent on the nature, the number, and the linking position of glycosyl moieties controlling their amphiphilic characters.
© (1995) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Michel Momenteau, Dalila Oulmi, Philiippe Maillard, Alain F. Croisy, "In vitro photobiological activity of a new series of photosensitizers: the glycoconjugated porphyrins", Proc. SPIE 2325, Photodynamic Therapy of Cancer II, (12 January 1995); doi: 10.1117/12.199141; https://doi.org/10.1117/12.199141
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