12 January 1995 New fluorinated photosensitizers based on tetrakis(hydroxyphenyl) porphyrins
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Proceedings Volume 2325, Photodynamic Therapy of Cancer II; (1995) https://doi.org/10.1117/12.199138
Event: International Symposium on Biomedical Optics Europe '94, 1994, Lille, France
Abstract
The potential advantages of fluorinated porphyrin photosensitizers are outlined. The syntheses of fluorinated analogues of sensitizers which are known to be active in vivo are described with particular reference to compounds of the tetrakis(hydroxyphenyl)porphyrin series. Three new fluorinated (hydroxyphenyl)porphyrins are prepared [5,10,15,20-tetrakis(2-fluoro-3- hydroxyphenyl)porphyrin; 5,10,15,20-tetrakis(2,4-difluoro-3-hydroxyphenyl)porphyrin; and 5,10,15,20-tetrakis(3,5-difluoro-4-hydroxyphenyl)porphyrin], and some of their relevant properties are described.
© (1995) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Raymond Bonnett, Raymond Bonnett, S. Phinda Songca, S. Phinda Songca, "New fluorinated photosensitizers based on tetrakis(hydroxyphenyl) porphyrins", Proc. SPIE 2325, Photodynamic Therapy of Cancer II, (12 January 1995); doi: 10.1117/12.199138; https://doi.org/10.1117/12.199138
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