Measurements of the optical properties of breast tissue using time-resolved transillumination

Jochen G. Koelzer; Gerhard Mitic; Johann Otto; Wolfgang Zinth

doi:10.1117/12.200841

31 January 1995 Measurements of the optical properties of breast tissue using time-resolved transillumination

Jochen G. Koelzer, Gerhard Mitic, Johann Otto, Wolfgang Zinth

Proceedings Volume 2326, Photon Transport in Highly Scattering Tissue; (1995) https://doi.org/10.1117/12.200841
Event: International Symposium on Biomedical Optics Europe '94, 1994, Lille, France

Abstract

Time-resolved in vivo measurements have been performed to determine the optical properties of the female breast. The optical parameters at 800 nm are of special interest for medical diagnosis since this wavelength is close to the isosbestic point of oxy- and deoxyhemoglobin. The measurements have been performed with a Ti:sapphire laser using a synchroscan-streak camera. The diffusion model has been used to calculate the absorption coefficient (mu) _A and the reduced scattering coefficient (mu) '_s equals (mu) _s (1 - g). Measurements at different positions on the mamma showed systematic changes of the time-resolved signals which can be explained by the composition of this heterogenous tissue. A good agreement between the measurements on the right and left mamma has been found. Additionally, time- resolved experiments on breast tissue in vitro at 532 nm, 800 nm, and 1064 nm have been performed to study the optical properties at these wavelengths.

Citation Download Citation

Jochen G. Koelzer, Gerhard Mitic, Johann Otto, and Wolfgang Zinth "Measurements of the optical properties of breast tissue using time-resolved transillumination", Proc. SPIE 2326, Photon Transport in Highly Scattering Tissue, (31 January 1995); https://doi.org/10.1117/12.200841

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