23 December 1994 Laser scanning endoscope via an imaging fiber bundle for fluorescence imaging
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Proceedings Volume 2327, Medical Applications of Lasers II; (1994) https://doi.org/10.1117/12.197605
Event: International Symposium on Biomedical Optics Europe '94, 1994, Lille, France
Abstract
Based on a laser scanning endoscope via an imaging fiber bundle, a new approach for a tumor diagnostic system has been developed to assist physicians in the diagnosis before the actual PDT is carried out. Laser induced, spatially resolved fluorescence images of diseased tissue can be compared with images received by video endoscopy using a white light source. The set- up is required to produce a better contrast between infected and healthy tissue and might serve as a constructive diagnostic help for surgeons. The fundamental idea is to scan a low-power laser beam on an imaging fiber bundle and to achieve a spatially resolved projection on the tissue surface. A sufficiently high laser intensity from the diode laser is concentrated on each single spot of the tissue exciting fluorescence when a dye has previously been accumulated. Subsequently, video image of the tissue is recorded and stored. With an image processing unit, video and fluorescence images are overlaid producing a picture of the fluorescence intensity in the environment of the observed tissue.
© (1994) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Lorenz D. Yeboah, Lorenz D. Yeboah, Dirk Nestler, Dirk Nestler, Rudolf W. Steiner, Rudolf W. Steiner, "Laser scanning endoscope via an imaging fiber bundle for fluorescence imaging", Proc. SPIE 2327, Medical Applications of Lasers II, (23 December 1994); doi: 10.1117/12.197605; https://doi.org/10.1117/12.197605
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