In vivo optical coherence tomography and topography of the fundus of the human eye

Wolfgang Drexler; Christoph K. Hitzenberger; Harald Sattmann; Adolf Friedrich Fercher

doi:10.1117/12.199257

12 January 1995 In vivo optical coherence tomography and topography of the fundus of the human eye

Wolfgang Drexler, Christoph K. Hitzenberger, Harald Sattmann, Adolf Friedrich Fercher

Proceedings Volume 2330, Lasers in Ophthalmology II; (1995) https://doi.org/10.1117/12.199257
Event: International Symposium on Biomedical Optics Europe '94, 1994, Lille, France

Abstract

The dual beam scanning partial coherence interferometry technique, which was recently developed to measure the fundus profile of the human eye in vivo, is used for tomographic and topographic imaging and for the measurement of different retinal structures, e.g., the contour of the papilla and thickness profiles of retina and retinal nerve fiber layer. In case of well defined, sharp boundaries between two layers of different refractive indices, the absolute position of these retinal structures can be determined with a precision (standard deviation) of 5 micrometers . Compared to first results with this instrument, the measurement time for horizontal and vertical scans was reduced by a factor of 10. At present, the measuring time of a vertical scan over 10 degree(s) in steps of 0.5 degree(s) takes at least 20 seconds without and 80 seconds with signal averaging of 4 longitudinal scans over 1.5 mm distance. Further improvements to 5 - 20 seconds are discussed. The longitudinal resolution of this instrument is approximately 15 micrometers (full-width-half-maximum), depending on the coherence length of the light source; this is about 5 times better than previous measurements. Topographic and tomographic scans across the optic disk reveal an increase of thickness of the retinal nerve fiber layer at the inferior and superior rim of the disk, which are in good agreement with results published in the literature.

Citation Download Citation

Wolfgang Drexler, Christoph K. Hitzenberger, Harald Sattmann, and Adolf Friedrich Fercher "In vivo optical coherence tomography and topography of the fundus of the human eye", Proc. SPIE 2330, Lasers in Ophthalmology II, (12 January 1995); https://doi.org/10.1117/12.199257

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