Information content in spectral dependencies of optical unit volume parameters under action of He-Ne laser on blood

Alphiya Ya. Khairullina; Tatiana V. Oleinik

doi:10.1117/12.197484

2 January 1995 Information content in spectral dependencies of optical unit volume parameters under action of He-Ne laser on blood

Alphiya Ya. Khairullina, Tatiana V. Oleinik

Author Affiliations +

Proceedings Volume 2370, 5th International Conference on Laser Applications in Life Sciences; (1995) https://doi.org/10.1117/12.197484
Event: Laser Applications in Life Sciences: 5th International Conference, 1994, Minsk, Belarus

Abstract

Our previous works concerned with the development of methods for studying blood and action of low-intensity laser radiation on blood and erythrocyte suspensions had shown the light- scattering methods gave a large body of information on a medium studied due to the methodological relationship between irradiation processes and techniques for investigations. Detail analysis of spectral diffuse reflectivities and transmissivities of optically thick blood layers, spectral absorptivities calculated on this basis over 600 - 900 nm, by using different approximations, for a pathological state owing to hypoxia testifies to the optical significance of not only hemoglobin derivatives but also products of hemoglobin decomposition. Laser action on blood is specific and related to an initial state of blood absorption due to different composition of chromoproteids. This work gives the interpretation of spectral observations. Analysis of spectral dependencies of the exinction coefficient e, mean cosine m of phase function, and parameter Q equals (epsilon) (1-(mu) )H/(lambda) (H - hematocrit) testifies to decreasing the relative index of refraction of erythrocytes and to morphological changes during laser action under pathology owing to hypoxia. The possibility to obtain physical and chemical information on the state of blood under laser action in vivo is shown to be based on the method proposed by us for calculating multilayered structures modeling human organs and on the technical implementation of this method.

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Alphiya Ya. Khairullina and Tatiana V. Oleinik "Information content in spectral dependencies of optical unit volume parameters under action of He-Ne laser on blood", Proc. SPIE 2370, 5th International Conference on Laser Applications in Life Sciences, (2 January 1995); https://doi.org/10.1117/12.197484

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