2 January 1995 Molecular mechanisms of DNA photocleavage by laser
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Proceedings Volume 2370, 5th International Conference on Laser Applications in Life Sciences; (1995) https://doi.org/10.1117/12.197488
Event: Laser Applications in Life Sciences: 5th International Conference, 1994, Minsk, Belarus
Abstract
The laser action on chromosomes of living cells in the presence and absence of exogenous chromophore (ethydium bromide) was studied. Also investigated was the possible role of the endogenous chromophores, such as riboflavin, in this mutagenic action. We show that riboflavin induces DNA strand cleavages at N2-laser irradiation. First the nonlinear mechanism of DNA cleavage by laser in the presence of riboflavin has been proven. Quantum yield of DNA strand cleavages by laser in the presence of riboflavin has been calculated.
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Sergei Khrapunov, Anatolii Dragan, Boris Pavlik, Nikolai Zubrilin, "Molecular mechanisms of DNA photocleavage by laser", Proc. SPIE 2370, 5th International Conference on Laser Applications in Life Sciences, (2 January 1995); doi: 10.1117/12.197488; https://doi.org/10.1117/12.197488
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