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1 March 1995 Intracellular uptake kinetics of hypocrellin photosensitizers for photodynamic therapy
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Proceedings Volume 2371, 5th International Photodynamic Association Biennial Meeting; (1995) https://doi.org/10.1117/12.203432
Event: Fifth International Photodynamic Association Biennial Meeting, 1994, Amelia Island, FL, United States
Abstract
Hypocrellins are naturally occurring compounds with photosensitizing properties in biological systems. We have prepared synthetic derivatives of hypocrellin B, which have promise as photosensitizers in the clinical application of photodynamic therapy. The inherent fluorescence of four selected compounds has provided a means of determining their uptake and distribution in monolayer cultures of EMT6/Ed murine tumor cells, via fluorescence confocal microscopy.
© (1995) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Gerald G. Miller, Kevin Brown, Ronald B. Moore, Zhenjun Diwu, Jixiang Liu, Liren Huang, J. William Lown, David A. Begg, Vera Chlumecky, John Tulip, and Malcolm S. McPhee "Intracellular uptake kinetics of hypocrellin photosensitizers for photodynamic therapy", Proc. SPIE 2371, 5th International Photodynamic Association Biennial Meeting, (1 March 1995); https://doi.org/10.1117/12.203432
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