Simple red light sources for photodynamic therapy of malignant tumors

K. S. Low; H. K. Chan; A. S. Haji Baba; C. H. Yip; K. W. Chang; Y. L. Lo; P. Jayalakshmi; L. M. Looi

doi:10.1117/12.203396

1 March 1995 Simple red light sources for photodynamic therapy of malignant tumors

K. S. Low, H. K. Chan, A. S. Haji Baba, C. H. Yip, K. W. Chang, Y. L. Lo, P. Jayalakshmi, L. M. Looi

Proceedings Volume 2371, 5th International Photodynamic Association Biennial Meeting; (1995) https://doi.org/10.1117/12.203396
Event: Fifth International Photodynamic Association Biennial Meeting, 1994, Amelia Island, FL, United States

Abstract

While laser beams are essential for endoscopic photodynamic therapy (PDT), many types of superficial tumors can be treated effectively using incoherent light sources which are appropriately filtered. This paper reports on clinical trials using simple and effective red light sources modified from an overhead projector and a surgical headlamp with fiber optic output. More than 1 W of effective red light can be obtained and used effectively in the palliative control of large superficial lesions in initial trial cases of three types of malignancies. The use of simple light sources for the treatment of superficial tumors avoids the technical complexities associated with laser sources and enables ready observations of treatment response. Such clinical trials should be conducted extensively in the development of PDT as a viable cancer treatment modality prior to the development of endoscopic procedures.

Citation Download Citation

K. S. Low, H. K. Chan, A. S. Haji Baba, C. H. Yip, K. W. Chang, Y. L. Lo, P. Jayalakshmi, and L. M. Looi "Simple red light sources for photodynamic therapy of malignant tumors", Proc. SPIE 2371, 5th International Photodynamic Association Biennial Meeting, (1 March 1995); https://doi.org/10.1117/12.203396

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