1 March 1995 Tumor-localizing fluorescent diagnostic agents without phototoxicity: HAT-D01
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Proceedings Volume 2371, 5th International Photodynamic Association Biennial Meeting; (1995) https://doi.org/10.1117/12.203442
Event: Fifth International Photodynamic Association Biennial Meeting, 1994, Amelia Island, FL, United States
Abstract
In order to develop tumor-localizing fluorescent diagnostic agents without phototoxicity, various heterodimers linked by some spacers between a chlorine derivative and its Mn or Cu complex were synthesized. The representative agent of them was named HAT-DO1 and has a molecular formula of m-phthalyl-{[13,17-bispropanoic acid-3-ethenyl-8-formylethylidene-7- hydroxy-2,7,12,18-tetramethyl-porphyrinate]-manganese (III)]}-(3'-ethenyl-8'- formylethylidene-7'-hydroxy-2',7',12',18'-tetramethyl-porphine-13',17'- bispropanoyl aspartic acid)-bishydrazone.
© (1995) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Takeshi Takemura, Shiro Umeuchi, Susumu Nakajima, Isao Sakata, "Tumor-localizing fluorescent diagnostic agents without phototoxicity: HAT-D01", Proc. SPIE 2371, 5th International Photodynamic Association Biennial Meeting, (1 March 1995); doi: 10.1117/12.203442; https://doi.org/10.1117/12.203442
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