Spectral transillumination of human breast tissue

Hans Heusmann; Jochen G. Koelzer; Ralf Puls; Johann Otto; Sylvia Heywang-Koebrunner; Wolfgang Zinth

doi:10.1117/12.210023

30 May 1995 Spectral transillumination of human breast tissue

Hans Heusmann, Jochen G. Koelzer, Ralf Puls, Johann Otto, Sylvia Heywang-Koebrunner, Wolfgang Zinth

Proceedings Volume 2389, Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media: Theory, Human Studies, and Instrumentation; (1995) https://doi.org/10.1117/12.210023
Event: Photonics West '95, 1995, San Jose, CA, United States

Abstract

By transilluminating human tissue in vivo in the visible and near-IR regions, specific information can be obtained in utilizing both the scattering and the absorbing properties of light. Different compositions of fatty, fibrous, glandular, and muscular tissues are associated with different optical parameters (reduced scattering and absorption coefficients). To characterize human breast tissue in vivo, measurements were carried out in a clinical environment. Thus the tissues, which showed a variety of pathalogical alteration, where measured in patients with different age, different breast size, in varying locations in the breast. The results indicate that other characteristics beyond the pure detection of the amount of blood in the neovascular network, in particular the volume concentrations of water and fat, seem to be important for the discrimination. In order to quantify this observation, an analytical model was developed that takes the volume percentages of fat and water, the concentration and oxygenation of hemoglobin, and the relevant optical coefficients into account. The in vivo spectra could be fitted in all cases. Typical results will be discussed and preliminary statistical correlations presented.

Citation Download Citation

Hans Heusmann, Jochen G. Koelzer, Ralf Puls, Johann Otto, Sylvia Heywang-Koebrunner, and Wolfgang Zinth "Spectral transillumination of human breast tissue", Proc. SPIE 2389, Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media: Theory, Human Studies, and Instrumentation, (30 May 1995); https://doi.org/10.1117/12.210023

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available