Characterization of products of excimer laser ablation of collagen

Marwood N. Ediger; D. W. Hahn; George H. Pettit M.D.

doi:10.1117/12.209832

22 May 1995 Characterization of products of excimer laser ablation of collagen

Marwood N. Ediger, D. W. Hahn, George H. Pettit M.D.

Proceedings Volume 2393, Ophthalmic Technologies V; (1995) https://doi.org/10.1117/12.209832
Event: Photonics West '95, 1995, San Jose, CA, United States

Abstract

The presence of hydroxyl radicals in the ArF excimer ablation sites in bovine corneal tissue has been investigated by laser-induced fluorescence and Raman spectroscopy. Raman spectroscopy has also been applied to examine the time-resolved temperature of the water component of the ablation site as well as the spatially selective measurement of surface desiccation. Results indicate that the hydroxyl radical is not generate in abundance during the ablation process. Also, Raman monitoring of the ablation site demonstrates no detectable heating during ArF irradiation, while elevated temperatures are observed following exposure of the corneal surface to a Er:YAG laser. Finally, comparison of C-H and O-H Raman bands shows potential utility as a spatially selective means for monitoring tissue hydration.

Citation Download Citation

Marwood N. Ediger, D. W. Hahn, and George H. Pettit M.D. "Characterization of products of excimer laser ablation of collagen", Proc. SPIE 2393, Ophthalmic Technologies V, (22 May 1995); https://doi.org/10.1117/12.209832

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