12 May 1995 Comparison of the extent of Nd:YAG and diode (810 nm) laser-induced thermal coagulation of human prostate: a histopathological analysis of acute response
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Abstract
The objective of the study was to compare the extent of thermocoagulation induced in the human prostate by two regimens of Nd:YAG laser (50 W X 60 s and 15 W X 180 s) and one regimen of diode (810 nm) laser (15 W X 180 s). Powers were measured at the fiber tip. The study was conducted in 6 patients undergoing radical prostatectomy because of malignancy whose prostates were treated transurethrally with laser radiation at the time of the procedure. The prostate specimens were retrieved approximately 90 minutes after laser treatment, and then prepared for histological examination. In all the cases, the diode laser was applied to the left side of the prostate and the Nd:YAG laser (either regimen) to the right side, in order to prevent treatment variables related to histological composition. Coagulation necrosis was confined within the transition zone in all the case and at times BPH was unaffected, if nodular. Similar depth of coagulation was observed for both Nd:YAG regimens (mean 12 mm, range 10 to 14) and the depth of coagulation was slightly less for the diode laser (mean 10.6 mm, range 8 to 14). Our results suggest that, at the studied dosimetries, the thermocoagulation effect of diode laser in the human prostate approximates to that seen with Nd:YAG laser.
© (1995) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Eduardo Orihuela, Eduardo Orihuela, Mariela Pow-Sang, Mariela Pow-Sang, Steve Johnson, Steve Johnson, Daniel Cowan, Daniel Cowan, Michael M. Warren, Michael M. Warren, Massoud Motamedi, Massoud Motamedi, } "Comparison of the extent of Nd:YAG and diode (810 nm) laser-induced thermal coagulation of human prostate: a histopathological analysis of acute response", Proc. SPIE 2395, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems V, (12 May 1995); doi: 10.1117/12.209083; https://doi.org/10.1117/12.209083
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