7 April 1995 Visualizing the anatomical-functional correlation of the human brain
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Abstract
Three-dimensional tomographic images obtained from different modalities or from the same modality at different times provide complementary information. For example, while PET shows brain function, images from MRI identify anatomical structures. In this paper, we investigate the problem of displaying available information about structures and function together. Several steps are described to achieve our goal. These include segmentation of the data, registration, resampling, and display. Segmentation is used to identify brain tissue from surrounding tissues, especially in the MRI data. Registration aligns the different modalities as closely as possible. Resampling arises from the registration since two data sets do not usually correspond and the rendering method is most easily achieved if the data correspond to the same grid used in display. We combine several techniques to display the data. MRI data is reconstructed from 2D slices into 3D structures from which isosurfaces are extracted and represented by approximating polygonalizations. These are then displayed using standard graphics pipelines including shaded and transparent images. PET data measures the qualitative rates of cerebral glucose utilization or oxygen consumption. PET image is best displayed as a volume of luminous particles. The combination of both display methods allows the viewer to compare the functional information contained in the PET data with the anatomically more precise MRI data.
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YuKuang Chang, YuKuang Chang, Alyn P. Rockwood, Alyn P. Rockwood, Eric M. Reiman, Eric M. Reiman, } "Visualizing the anatomical-functional correlation of the human brain", Proc. SPIE 2410, Visual Data Exploration and Analysis II, (7 April 1995); doi: 10.1117/12.205980; https://doi.org/10.1117/12.205980
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