Most real time CCD video cameras are designed to operate on TV format. However, TV format CCD cameras have some basic limitations in many applications due to the interlace scanning, limited horizontal scanning lines per frame and relatively low scanning speed. Non-TV format cameras have now been developed based on progressive scan interline transfer CCDs in order to optimize performance in high speed machine vision, electronic shutter applications, dynamic motion frame capturing, high resolution real time imaging and direct computer interface applications. The simultaneous exposure of all pixels and the structure of the substrate drain mechanism make it possible to operate the high speed electronic shutter with full frame resolution and uniform long integration. The digital processing, built-in frame memory and output format are described herein for asynchronous reset and image capturing, long integration image capturing, and scan conversion. The noise characteristics and the specific CCD characteristics during high speed electronic shutter are studied from a camera design standpoint. A Peltier-cooled CCD camera and an image intensifier-to-camera coupling are studied for real time, high resolution fluorescent microscopy applications. A progressive scan color camera is also described. The CCD color filter, color processing (digital processing), and output format are discussed.