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24 May 1995 In-vivo assessment of perfusion: methods and pitfalls
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Imaging methods that have relatively high scan repetition rates can be used to generate indicator dilution curves in spatially defined regions of interest. This image-based analysis of indicator dilution processes has several potential advantages over catheter sampled indicator curve analysis. These include the fact that sampling can be performed in many locations within the vascular system where sampling catheters cannot be placed. Moreover, the multitudes of simultaneous sampling sites that can be accessed with CT would be prohibitively invasive if performed by multiple sampling catheters. Image—based indicator dilution curve analysis does have several limitations and/or special considerations that must be acknowledged and dealt with. It is the purpose of this workshop to highlight some of these special issues and to explore solutions to them. These issues indicate that use of these techniques requires consideration of the application as well as the imaging method.
© (1995) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Erik Leo Ritman M.D. "In-vivo assessment of perfusion: methods and pitfalls", Proc. SPIE 2433, Medical Imaging 1995: Physiology and Function from Multidimensional Images, (24 May 1995);

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