NIFTY (NeuroImaging Functional Toolkit) is a tool designed to perform quantitative analysis and visualization of neurofunctional magnetic resonance image (fMRI) data sets. NIFTY is an OSF/Motif application which utilizes the AVW (a visualization workshop) imaging library developed in our laboratory and includes algorithms for robust image registration, statistical analysis, and mapping of neurofunctional data sets. Anisotropic diffusion routines can be used to enhance the signal-to-noise- ratio of these images. Tools capable of histogram equalization, thresholding, volume rendering, atlas matching, and a large number of other functions can then be used to visualize the data. NIFTY's development will offer a robust and flexible system of essential functions integrated into an interactive, graphically-oriented program, allowing neuroscientists the means by which to process, visualize, and interpret their data.