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24 May 1995 Use of multidimensional, multimodal imaging and PACS to support neurological diagnoses
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Technological advances in brain imaging have revolutionized diagnosis in neurology and neurological surgery. Major imaging techniques include magnetic resonance imaging (MRI) to visualize structural anatomy, positron emission tomography (PET) to image metabolic function and cerebral blood flow, magnetoencephalography (MEG) to visualize the location of physiologic current sources, and magnetic resonance spectroscopy (MRS) to measure specific biochemicals. Each of these techniques studies different biomedical aspects of the brain, but there lacks an effective means to quantify and correlate the disparate imaging datasets in order to improve clinical decision making processes. This paper describes several techniques developed in a UNIX-based neurodiagnostic workstation to aid the noninvasive presurgical evaluation of epilepsy patients. These techniques include online access to the picture archiving and communication systems (PACS) multimedia archive, coregistration of multimodality image datasets, and correlation and quantitation of structural and functional information contained in the registered images. For illustration, we describe the use of these techniques in a patient case of nonlesional neocortical epilepsy. We also present out future work based on preliminary studies.
© (1995) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Stephen T. C. Wong, Robert C. Knowlton M.D., Kent Soo Hoo, and H. K. Huang "Use of multidimensional, multimodal imaging and PACS to support neurological diagnoses", Proc. SPIE 2433, Medical Imaging 1995: Physiology and Function from Multidimensional Images, (24 May 1995);

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