12 May 1995 Improved image processing techniques for multiple-angle x-ray bone densitometry
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Abstract
A method utilizing digital dual-energy substraction x-ray radiography for measuring calcium densities localized to the cortical and cancellous regions of bone cross sections is described. The method is proposed as a technique for studying calcium loss in femurs of rats used in experiments modeling the temporal of osteoporosis. The densitometry data obtained for a rat leg consists of six x-ray projection images acquired at 30 degree(s) angular intervals about the bone axis by an intensifying screen/CCD camera imaging system. Images of bone cross sections are reconstructed by application of a maximum entropy algorithm constrained by the six projection images. The observed density data are further discriminated into cortical, cancellous and external regions on the basis of reference levels found on image density histograms.
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Lawrence M. Jordan, Li Gao, Peter G. Davis, Frank A. DiBianca, Jeno I. Sebes, Donald B. Thomason, Herbert D. Zeman, Gunnar Lovhoiden, "Improved image processing techniques for multiple-angle x-ray bone densitometry", Proc. SPIE 2434, Medical Imaging 1995: Image Processing, (12 May 1995); doi: 10.1117/12.208724; https://doi.org/10.1117/12.208724
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