Detection of small trace molecules in human and animal's exhalation by tunable diode lasers

Eugene V. Stepanov; Andrian I. Kouznetsov; Pavel V. Zyrianov; Vladimir A. Skrupskii; Yurii A. Shulagin; Marina E. Galagan

doi:10.1117/12.221088

21 September 1995 Detection of small trace molecules in human and animal exhalation by tunable diode lasers

Eugene V. Stepanov, Andrian I. Kouznetsov, Pavel V. Zyrianov, Vladimir A. Skrupskii, Yurii A. Shulagin, Marina E. Galagan

Author Affiliations +

Proceedings Volume 2503, Air Toxics and Water Monitoring; (1995) https://doi.org/10.1117/12.221088
Event: European Symposium on Optics for Environmental and Public Safety, 1995, Munich, Germany

Abstract

Tunable diode laser spectroscopy (TDLS) is proposed for content measurements of trace gases like CO, CO₂, NH₃, CH₄, NO, NO₂ in human and animal's exhalation. High sensitivity and wide dynamic range of the method ensure fast detection of these gases at ppb level and within the accuracy better than 10%. One-expiration sample is enough to reach these parameters. There is no need for any preliminary preparation of tested samples. Some pairs of the gases, for instance, CO and CO₂, NH₃, and CO₂, and CO and N₂O, can be measured simultaneously by one laser providing complex studies. The high sensitive gas analysis could provide necessary background to the noninvasive diagnostics in a wide variety of medical problems. Perspectives of the TDLS methods in application to medicine diagnostics are demonstrated by the first results of exhalation tests.

Citation Download Citation

Eugene V. Stepanov, Andrian I. Kouznetsov, Pavel V. Zyrianov, Vladimir A. Skrupskii, Yurii A. Shulagin, and Marina E. Galagan "Detection of small trace molecules in human and animal exhalation by tunable diode lasers", Proc. SPIE 2503, Air Toxics and Water Monitoring, (21 September 1995); https://doi.org/10.1117/12.221088

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