End-to-end microvascular anastomoses with a 1.9-un diode laser

Serge R. Mordon; Veronique L. Martinot; Valerie A. Mitchell

doi:10.1117/12.230346

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19 January 1996 End-to-end microvascular anastomoses with a 1.9-un diode laser

Serge R. Mordon, Veronique L. Martinot, Valerie A. Mitchell

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Proceedings Volume 2623, Medical Applications of Lasers III; (1996) https://doi.org/10.1117/12.230346
Event: BiOS Europe '95, 1995, Barcelona, Spain

Abstract

This in-vivo study examines the interest of vessel anastomosis with a 1.9 micrometer diode laser. Ten end-to-end carotid anastomoses and 10 end-to-end jugular anastomoses are performed in Wistar rats. The technique requires brief applications (20 to 25 spots) with a diode laser (lambda equals 1.9 micrometer, (phi) equals 220 micrometer, P equals 60 mW, t equals 0.7 s, F equals 110 J/cm²) after placement of three equidistant stay sutures. The macroscopic aspect and patency are evaluated at different post-operative intervals. Vessel histology is performed at 15, 21, and 30 days after the procedure. These anastomoses reveal minimal thermal damage in the adventitial layer only at depth of 200 micrometer. No medial or intimal thermal damage is identified. No thrombosis is observed, giving a permeability of 100% for both arteries and veins. The mean clamping time is 9 plus or minus 3 min. For 1.9 micrometer, the water extinction length is 0.15 mm. The welded thickness is comparable to the extinction length of the wavelength giving consequently a weld strength of 4 multiplied by 10⁶ dynes/cm² comparable to the strength of suture repairs: 5 - 6 multiplied by 10⁶ dynes/cm². These findings suggest that a low-energy 1.9 micrometer diode laser has potential clinical application for anastomosis of small vessels.

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Serge R. Mordon, Veronique L. Martinot, and Valerie A. Mitchell "End-to-end microvascular anastomoses with a 1.9-un diode laser", Proc. SPIE 2623, Medical Applications of Lasers III, (19 January 1996); https://doi.org/10.1117/12.230346

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