19 January 1996 Lesion size produced by interstitial laser coagulation: cylindrical diffuser versus bare-tip fiber
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Abstract
Interstitial laser coagulation is a new method of localized tissue destruction that may be used to eliminate solid tumors, such as hepatic metastases, an in-vitro study was performed to compare a cylindrical diffusing-tip (length 2 cm) with a bare-tip fiber. Fiber ends were positioned between two porcine liver slabs (37 degrees Celsius) and Nd:YAG laser light (1064 nm) was guided through either fiber with an output of 3 - 9 W and exposure times of 6 - 18 minutes. Lesions produced by the cylindrical diffuser-tip were significantly larger and more predictable at a higher laser output (greater than 6 W). With the diffuser tip lesions up to 36 mm in length and 23 mm in width could be produced at 7 W and 9 min without any central charring. Lesions produced with the bare-tip fiber were up to 32 mm in length and 20 mm in width at 6 W and 9 min with massive charring. These results indicate that at optimal laser settings the diffuser of 2 cm length produces a larger coagulation volume than a point light source and that charring should be avoided in interstitial laser coagulation.
© (1996) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Joos Heisterkamp, Richard van Hillegersberg, Jan N. M. IJzermans, "Lesion size produced by interstitial laser coagulation: cylindrical diffuser versus bare-tip fiber", Proc. SPIE 2623, Medical Applications of Lasers III, (19 January 1996); doi: 10.1117/12.230336; https://doi.org/10.1117/12.230336
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