Physical modeling of human skin optical properties using milk and erythrocytes mixtures

Alexander B. Pravdin; Sergei R. Utz M.D.; Vyacheslav I. Kochubey

doi:10.1117/12.228896

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27 December 1995 Physical modeling of human skin optical properties using milk and erythrocytes mixtures

Alexander B. Pravdin, Sergei R. Utz M.D., Vyacheslav I. Kochubey

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Proceedings Volume 2627, Optical Biopsies; (1995) https://doi.org/10.1117/12.228896
Event: BiOS Europe '95, 1995, Barcelona, Spain

Abstract

We offer a two-layer dermis-like model phantom with controlled concentration of absorbers and scatterers; namely, the mixture of whole milk diluted with isotonic solution and suspension of washed human erythrocytes -- as one layer, and teflon base -- as another. The optimum milk dilution was determined, and wavelength dependencies of phantom remittance (R) over the range 480 - 680 nm were obtained. We use the mixtures with physiological concentrations of erythrocytes which corresponded to 2 - 18% per volume blood content in human papillary dermis and upper blood plexus. Phantom remittance spectra for the cases of 2% and 4% blood content virtually coincide with remittance spectra of normal and erythema human skin. Collimated transmittance (T) of blood-milk layer was also measured. At 500 nm we estimated the range of linearity of D and D' (D equals $min1gT, D' equals -1gR) dependence on blood content: offset from linearity was observed near 5 - 6% and 10% of blood, respectively.

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Alexander B. Pravdin, Sergei R. Utz M.D., and Vyacheslav I. Kochubey "Physical modeling of human skin optical properties using milk and erythrocytes mixtures", Proc. SPIE 2627, Optical Biopsies, (27 December 1995); https://doi.org/10.1117/12.228896

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