27 December 1995 Physical modeling of human skin optical properties using milk and erythrocytes mixtures
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Abstract
We offer a two-layer dermis-like model phantom with controlled concentration of absorbers and scatterers; namely, the mixture of whole milk diluted with isotonic solution and suspension of washed human erythrocytes -- as one layer, and teflon base -- as another. The optimum milk dilution was determined, and wavelength dependencies of phantom remittance (R) over the range 480 - 680 nm were obtained. We use the mixtures with physiological concentrations of erythrocytes which corresponded to 2 - 18% per volume blood content in human papillary dermis and upper blood plexus. Phantom remittance spectra for the cases of 2% and 4% blood content virtually coincide with remittance spectra of normal and erythema human skin. Collimated transmittance (T) of blood-milk layer was also measured. At 500 nm we estimated the range of linearity of D and D' (D equals $min1gT, D' equals -1gR) dependence on blood content: offset from linearity was observed near 5 - 6% and 10% of blood, respectively.
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Alexander B. Pravdin, Alexander B. Pravdin, Sergei R. Utz, Sergei R. Utz, Vyacheslav I. Kochubey, Vyacheslav I. Kochubey, } "Physical modeling of human skin optical properties using milk and erythrocytes mixtures", Proc. SPIE 2627, Optical Biopsies, (27 December 1995); doi: 10.1117/12.228896; https://doi.org/10.1117/12.228896
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