15 January 1996 Lymph-flow diagnostics using speckle microscopy
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Abstract
In the present paper speckle-interferometrical technique utilizing strongly focused Gaussian beam (SFGB) diffraction has been proposed for the analysis of microcirculatory parameters. The method has been applied for the investigation of lymph motion characteristics in microvessels in vivo. Spectra of scattered intensity fluctuations in the statistically inhomogeneous speckles formed at the diffraction in lymph microvessels have been presented. It has been shown that the alterations of the spectra envelope depend on peculiarities of lymph motion in microvessels. Physical parameters of determination both of temporal changes of a mean velocity and of spatial-temporal velocity distribution in lymph microvessels have been proposed. An application of lymphotropic drug on the lymph microvessels has been studied. Temporal changes of lymph flow parameters have been analyzed in the paper.
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Andrey A. Bednov, Andrey A. Bednov, Valery V. Tuchin, Valery V. Tuchin, Sergey S. Ulyanov, Sergey S. Ulyanov, Gregory E. Brill, Gregory E. Brill, Ekateryna I. Galanzha, Ekateryna I. Galanzha, } "Lymph-flow diagnostics using speckle microscopy", Proc. SPIE 2630, Effects of Low-Power Light on Biological Systems, (15 January 1996); doi: 10.1117/12.230037; https://doi.org/10.1117/12.230037
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