Integrated optics in biosensor design

Jukka Lekkala; Janusz W. Sadowski; Jyrki S. Kimmel; Pekka Katila; Jaakko Aarnio

doi:10.1117/12.229168

3 January 1995 Integrated optics in biosensor design

Jukka Lekkala, Janusz W. Sadowski, Jyrki S. Kimmel, Pekka Katila, Jaakko Aarnio

Proceedings Volume 2631, Medical and Fiber Optic Sensors and Delivery Systems; (1995) https://doi.org/10.1117/12.229168
Event: BiOS Europe '95, 1995, Barcelona, Spain

Abstract

Optical sensing techniques have obtained remarkable attention in developing biosensors. Especially, methods based on evanescent field probing are suitable for direct immunosensing. However, miniaturized immunosensors are more difficult to realize when compared with catalytic sensors. Miniaturization and the small amounts of reagents will speed up detection but they are also a potential source of errors and instability. Different aspects of miniaturization of immunosensors are discussed. Some modeling methods of the optical biosensing interface are presented. Modeling is important, but there is a lack of detailed optical data of biomolecules. Two integrated optics detectors are described and their use in biosensing applications are evaluated.

Citation Download Citation

Jukka Lekkala, Janusz W. Sadowski, Jyrki S. Kimmel, Pekka Katila, and Jaakko Aarnio "Integrated optics in biosensor design", Proc. SPIE 2631, Medical and Fiber Optic Sensors and Delivery Systems, (3 January 1995); https://doi.org/10.1117/12.229168

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