Detecting lesions in magnetic resonance breast scans

Rakesh Kumar; Keith Hanna; J. Charles Asmuth; James R. Bergen; C. Hulka; Daniel B. Kopans; R. Weisskoff; Richard H. Moore

doi:10.1117/12.233064

19 February 1996 Detecting lesions in magnetic resonance breast scans

Rakesh Kumar, Keith Hanna, J. Charles Asmuth, James R. Bergen, C. Hulka, Daniel B. Kopans, R. Weisskoff, Richard H. Moore

Author Affiliations +

Proceedings Volume 2645, 24th AIPR Workshop on Tools and Techniques for Modeling and Simulation; (1996) https://doi.org/10.1117/12.233064
Event: 24th AIPR Workshop on Tools and Techniques for Modeling and Simulation, 1995, Washington, DC, United States

Abstract

In this paper we present 3D registration techniques for detecting breast cancer lesions based on differences between the high spatial resolution 'pre' and 'post' contrast administration MR breast scans. We also present registration techniques for detecting lesions based on the time course of enhancement after administration of the contrast agent based on changes in the low spatial resolution, high temporal resolution, dynamic MR data taken during the absorption of the contrast agent. Alignment of the 'pre' and 'post' MR data and of the dynamic MR images is done by a direct optimization technique to estimate a global affine deformation model using a coarse-to-fine control strategy over a 3D pyramid. This global model is followed by a one iteration flow estimation to account for any local non-rigidity. We present results of the registration process and visualization of the different volumes obtained after alignment.

Citation Download Citation

Rakesh Kumar, Keith Hanna, J. Charles Asmuth, James R. Bergen, C. Hulka, Daniel B. Kopans, R. Weisskoff, and Richard H. Moore "Detecting lesions in magnetic resonance breast scans", Proc. SPIE 2645, 24th AIPR Workshop on Tools and Techniques for Modeling and Simulation, (19 February 1996); https://doi.org/10.1117/12.233064

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