8 March 1996 GENVIS: a sequence visualization technique for genomic DNA
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Abstract
We describe a software platform in which large DNA sequence datasets may be visualized by techniques which readily reveal patterns and insights. Initially we have focused on providing accurate statistical visualizations rather than qualitative presentations. The first application of this platform visualizes properties of DNA sequence strings of any size as a function of string position (for example, in a large chromosome). We provide an example in which we visualize the ratio of found to expected frequency of occurrence for specific sequence strings (AAAA and TTTT) and show these reveal interesting patterns in that DNA string (yeast chromosome III). For flexibility, any new function, calculated from the sequence string, may be added to the software platform.
© (1996) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Ashish Mamania, Georges G. Grinstein, Kenneth A. Marx, "GENVIS: a sequence visualization technique for genomic DNA", Proc. SPIE 2656, Visual Data Exploration and Analysis III, (8 March 1996); doi: 10.1117/12.234669; https://doi.org/10.1117/12.234669
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